Molecular Formula | C257H383N65O77S6 |
Melting Point | >200°C (dec.) |
Water Solubility | Soluble up to 10mg/ml in pH <3 or in the presence of surfactants. Adjusting pH with a volatile acid (such as formic acid) prior to dry down will allow the product to be re-dissolved in water. |
Solubility | acidified water, pH2.0: 2mg/mL |
Appearance | solution |
Color | White |
Storage Condition | -20°C |
In vitro study | The human insulin gene contains two intervening sequences, one is within the region transcribed into the 5'-untranslated segment of the mRNA and the other interrupts the C-peptide encoding region. Human insulin is commonly used to treat type 2 diabetes. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
RTECS | NM8900250 |
FLUKA BRAND F CODES | 3-10 |
HS Code | 2937120000 |
Toxicity | LD50 intraperitoneal in mouse: 3937units/kg |
Overview | insulin glargine is an insulin analog that replaces a glycine, the addition of two arginine, therefore, is called insulin glargine, and the addition of these groups makes the solution of this drug clear under acidic conditions, and when injected subcutaneously into the human body, the neutral environment of the human body causes insulin glargine to form a fine precipitate, so that the drug is slowly released, similar to the physiological secretion of insulin in the human body, and can play a stable and effective role in controlling sugar for 24 hours. |
Use | insulin glargine is a new type of long-acting insulin analog, also known as basal insulin, injection once a day at a fixed time, for the control of fasting blood glucose and postprandial blood glucose, have a smooth sugar control effect. |
biological activity | human is a polypeptide hormone that regulates glucose levels. Insulin is commonly used to treat hyperglycemia in diabetic patients. potency: 29 units/mg. |